Obesity

Untertitel:epigenetic regulation – recent observations
Autoren:Remely, Marlene; de la Garza, Ana Laura; Magnet, Ulrich; Aumueller, Eva; Haslberger, Alexander G
Abstrakt:

Genetic and environmental factors, especially nutrition and lifestyle, have been discussed in the literature for their relevance to epidemic obesity. Gene-environment interactions may need to be understood for an improved understanding of the causes of obesity, and epigenetic mechanisms are of special importance. Consequences of epigenetic mechanisms seem to be particularly important during certain periods of life: prenatal, postnatal and intergenerational, transgenerational inheritance are discussed with relevance to obesity. This review focuses on nutrients, diet and habits influencing intergenerational, transgenerational, prenatal and postnatal epigenetics; on evidence of epigenetic modifiers in adulthood; and on animal models for the study of obesity.

Sprache:Englisch
Anzahl der Seiten:13
Publikationsdatum:6.2015
Journaltitel:Biomolecular concepts
Volume:6
Nummer:3
Seiten:163-75
Peer reviewed:true
Links:
Digital Object Identifier (DOI):http://dx.doi.org/10.1515/bmc-2015-0009
Publikationstyp:Artikel
Portal:https://ucris.univie.ac.at/portal/en/publications/obesity(97ddeb92-5bcf-4944-ad52-b5a87c9b3e2d).html