Nutriepigenomics

Untertitel:the role of nutrition in epigenetic control of human diseases
Autoren:Remely, Marlene; Stefanska, Barbara; Lovrecic, Luca; Magnet, Ulrich; Haslberger, Alexander G
Abstrakt:

PURPOSE OF REVIEW: Nutrients or even diets affect the epigenome by lifelong remodeling. Nutritional imbalances are associated with noncommunicable diseases. Thus, nutriepigenomics is a promising field in the treatment of complex human diseases.

RECENT FINDINGS: The epigenome is susceptible to changes and can be shaped by nutritional states, especially in prenatal period through transgenerational mechanisms and in early postnatal life when critical developmental processes are taking place. Although more stable, the epigenetic marks in adulthood are also dynamic and modifiable by environmental factors including diet.

SUMMARY: The present review is focused on the most recent knowledge of epigenetically active nutrients/diets including transgenerational inheritance and prenatal predispositions related to increased risk for cancer, metabolic syndrome, and neurodegenerative diseases.

Sprache:Englisch
Anzahl der Seiten:6
Publikationsdatum:7.2015
Journaltitel:Current opinion in clinical nutrition and metabolic care
Volume:18
Nummer:4
Seiten:328-33
Peer reviewed:true
Links:
Digital Object Identifier (DOI):http://dx.doi.org/10.1097/MCO.0000000000000180
Publikationstyp:Artikel
Portal:https://ucris.univie.ac.at/portal/en/publications/nutriepigenomics(c741d72d-49d1-4cfe-94d8-8f1081f4cbc2).html