Comparison of the long-term effects of high-fat v. low-fat diet consumption on cardiometabolic risk factors in subjects with abnormal glucose metabolism

Untertitel:a systematic review and meta-analysis
Autoren:Schwingshackl, Lukas (Universität Wien); Hoffmann, Georg (Universität Wien)
Abstrakt:The aim of the present systematic review and meta-analysis was to examine the long-term effects (>= 12 months) of high-fat (HF) v. low-fat (LF) diet consumption on the indicators of glycaemic control as well as cardiovascular risk factors in pre-diabetic and diabetic individuals. Literature search was carried out using the electronic databases MEDLINE, Embase and the Cochrane Trial Register until November 2013. Study-specific weighted mean differences (MD) were pooled using a random-effects model of the Cochrane software package Review Manager 5.1 and Stata 12.0 was used for meta-regressions. A total of fourteen trials met the inclusion criteria and a maximum of 1753 subjects were included in the meta-analysis. HF regimens were found to result in a significant decrease in TAG levels (MD - 0.19 mmol/l, 95 % CI -0.23, -0.14, P
Anzahl der Seiten:12
Journaltitel:British Journal of Nutrition
Peer reviewed:true
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