Nutriepigenomics

Autor(en)
Marlene Remely, Barbara Stefanska, Luca Lovrecic, Ulrich Magnet, Alexander G Haslberger
Abstrakt

PURPOSE OF REVIEW: Nutrients or even diets affect the epigenome by lifelong remodeling. Nutritional imbalances are associated with noncommunicable diseases. Thus, nutriepigenomics is a promising field in the treatment of complex human diseases.

RECENT FINDINGS: The epigenome is susceptible to changes and can be shaped by nutritional states, especially in prenatal period through transgenerational mechanisms and in early postnatal life when critical developmental processes are taking place. Although more stable, the epigenetic marks in adulthood are also dynamic and modifiable by environmental factors including diet.

SUMMARY: The present review is focused on the most recent knowledge of epigenetically active nutrients/diets including transgenerational inheritance and prenatal predispositions related to increased risk for cancer, metabolic syndrome, and neurodegenerative diseases.

Organisation(en)
Department für Ernährungswissenschaften
Externe Organisation(en)
Purdue University, University Medical Centre Ljubljana
Journal
Current opinion in clinical nutrition and metabolic care
Band
18
Seiten
328-333
Anzahl der Seiten
6
ISSN
1363-1950
DOI
https://doi.org/10.1097/MCO.0000000000000180
Publikationsdatum
07-2015
Peer-reviewed
Ja
ÖFOS 2012
303009 Ernährungswissenschaften
Schlagwörter
ASJC Scopus Sachgebiete
Nutrition and Dietetics, Medicine (miscellaneous)
Sustainable Development Goals
SDG 3 – Gesundheit und Wohlergehen
Link zum Portal
https://ucris.univie.ac.at/portal/de/publications/nutriepigenomics(c741d72d-49d1-4cfe-94d8-8f1081f4cbc2).html