Effects of dietary nitrate on inflammation and immune function, and implications for cardiovascular health
- Autor(en)
- Kyle Raubenheimer, Catherine Bondonno, Lauren Blekkenhorst, Karl-Heinz Wagner, Jonathan Peake, Oliver Neubauer
- Abstrakt
Inorganic dietary nitrate, found abundantly in green leafy and some root vegeta- bles, elicits several beneficial physiological effects, including a reduction in blood pressure and improvements in blood flow through nitrate–nitrite–nitric oxide sig- naling. Recent animal and human studies have shown that dietary nitrate and ni- trite also modulate inflammatory processes and immune cell function and pheno- types. Chronic low-grade inflammation and immune dysfunction play a critical role in cardiovascular disease. This review outlines the current evidence on the efficacy of nitrate-rich plant foods and other sources of dietary nitrate and nitrite to coun- teract inflammation and promote homeostasis of the immune and vascular systems. The data from these studies suggest that immune cells and immune– vasculature interactions are important targets for dietary interventions aimed at improving, preserving, or restoring cardiovascular health.
- Organisation(en)
- Department für Ernährungswissenschaften, Forschungsplattform Active Ageing
- Externe Organisation(en)
- Edith Cowan University, Queensland University of Technology
- Journal
- Nutrition Reviews
- ISSN
- 0029-6643
- Publikationsdatum
- 2019
- Peer-reviewed
- Ja
- ÖFOS 2012
- 303009 Ernährungswissenschaften
- Schlagwörter
- Sustainable Development Goals
- SDG 3 – Gesundheit und Wohlergehen
- Link zum Portal
- https://ucris.univie.ac.at/portal/de/publications/effects-of-dietary-nitrate-on-inflammation-and-immune-function-and-implications-for-cardiovascular-health(765f7378-026d-4d7a-9012-9f945d7eeba4).html