Effects of oils and solid fats on blood lipids

Autor(en)

Lukas Schwingshackl, Berit Bogensberger, Aleksander Benčič, Sven Knüppel, Heiner Boeing, Georg Hoffmann

Abstrakt

The aim of this network meta-analysis (NMA) is to compare the effects of different oils/solid fats on blood lipids. Literature searches were performed until March 2018. Inclusion criteria were as follows: i) randomized trial (3 weeks study length) comparing at least two of the following oils/solid fats: safflower, sunflower, rapeseed, hempseed, flaxseed, corn, olive, soybean, palm, and coconut oil, and lard, beef-fat, and butter; ii) outcomes LDL-cholesterol (LDL-C), total cholesterol (TC), HDL-cholesterol (HDL-C), and triacylglycerols (TGs). A random dose-response (per 10% isocaloric exchange) NMA was performed and surface under the cumulative ranking curve (SUCRA) was estimated. Fifty-four trials were included in the NMA. Safflower oil had the highest SUCRA value for LDL-C (82%) and TC (90%), followed by rapeseed oil (76% for LDL-C, 85% for TC); whereas, palm oil (74%) had the highest SUCRA value for TG, and coconut oil (88%) for HDL-C. Safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm, and coconut oil as well beef fat were more effective in reducing LDL-C (-0.42 to -0.23 mmol/l) as compared with butter. Despite limitations in these data, our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils.

Organisation(en)

Department für Ernährungswissenschaften

Externe Organisation(en)

Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIfE), NutriAct- Kompetenzcluster Ernährungsforschung Berlin-Potsdam, Universität Wien

Journal

Journal of Lipid Research

Band

59

Seiten

1771-1782

Anzahl der Seiten

12

ISSN

0022-2275

DOI

https://doi.org/10.1194/jlr.P085522

Publikationsdatum

09-2018

Peer-reviewed

Ja

ÖFOS 2012

303009 Ernährungswissenschaften

ASJC Scopus Sachgebiete

Endocrinology, Biochemistry, Cell Biology

Link zum Portal

https://ucris.univie.ac.at/portal/de/publications/effects-of-oils-and-solid-fats-on-blood-lipids(d3d483de-241d-4b5a-a2aa-6de1db254999).html