Effect of probiotic yoghurt on oxidant parameters and flavoproteins in healthy women

Elisabeth Fabian, Dorota Majchrzak, Ibrahim Elmadfa

Introduction: Considering that increased oxidative stress caused by enhanced immune functions leads to alterations in the enzymatic defends system and thereby to an increase of the flavoprotein turnover in human body we tried to examine to which extent daily consumption of probiotic or conventional yoghurt (as a good source of vitamin B2) has an influence on oxidant parameters and concentrations of flavoproteins (FAD, FMN) in plasma of healthy humans.

Subjects and design: After a preadjustment phase of 7d, female volunteers consumed 100g/d of a probiotic (probiotic group=PG: n=17) or conventional fermented yoghurt (conventional group=CG: n=16) for 14d (T1-T2) and 200g/d for another 14d (T2-T3). A wash-out phase lasting 14d followed.

Methods: Plasma concentrations of B2 vitamers (FAD, FMN), conjugated dienes (CD) and malondialdehyde (MDA) were analyzed using HPLC.

Results: During the period T1-T3 the depletion of several plasma antioxidants led to a significant increase of the average plasma levels of oxidant parameters as MDA and CD in the PG (MDA: pT3: p

Department für Ernährungswissenschaften
ÖFOS 2012
106002 Biochemie, 303009 Ernährungswissenschaften
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