Secundarellone A, B, and C from the leaves of Justicia secunda VAHL

Autor(en)

Barbara Theiler, Silvia Revoltella, Martin Zehl, Christina Dangl, Lugardo O Espinoza Caisa, Jürgen König, Johannes Winkler, Ernst Urban, Sabine Glasl

Abstrakt

The extract of the leaves of Justicia secunda VAHL (Acanthaceae) was subjected to column chromatography on Sephadex LH-20, silica gel, and RP-18e to yield a pure substance (1) and an equimolar mixture of diastereomers (2 and 3). MS and extensive NMR measurements led to the structure elucidation of these new N-arylpyrrolidones as 3-hydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (1), cis-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (2), and trans-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (3). They are named secundarellone A (1), B (2) and C (3) and are the first pyrrolidones isolated from the family of Acanthaceae.

Organisation(en)

Department für Ernährungswissenschaften

Externe Organisation(en)

Universität Wien, Corporación Verde Azul

Journal

Phytochemistry Letters

Band

10

Seiten

cxxix–cxxxii

Anzahl der Seiten

4

ISSN

1874-3900

DOI

https://doi.org/10.1016/j.phytol.2014.05.007

Publikationsdatum

05-2014

Peer-reviewed

Ja

ÖFOS 2012

301204 Pharmakognosie, 301207 Pharmazeutische Chemie, 303009 Ernährungswissenschaften

Schlagwörter

Link zum Portal

https://ucris.univie.ac.at/portal/de/publications/secundarellone-a-b-and-c-from-the-leaves-of-justicia-secunda-vahl(4fdceb74-4fec-45d8-8c00-1e4fd3217f95).html