Secundarellone A, B, and C from the leaves of Justicia secunda VAHL

Autor(en)

Barbara Theiler, Silvia Revoltella, Martin Zehl, Christina Dangl, Lugardo O Espinoza Caisa, Jürgen König, Johannes Winkler, Ernst Urban, Sabine Glasl

Abstrakt

The extract of the leaves of Justicia secunda VAHL (Acanthaceae) was subjected to column chromatography on Sephadex LH-20, silica gel, and RP-18e to yield a pure substance (1) and an equimolar mixture of diastereomers (2 and 3). MS and extensive NMR measurements led to the structure elucidation of these new N-arylpyrrolidones as 3-hydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (1), cis-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (2), and trans-3,5-dihydroxy-1-(2'-hydroxy-4',5'-dimethoxyphenyl)pyrrolidin-2-one (3). They are named secundarellone A (1), B (2) and C (3) and are the first pyrrolidones isolated from the family of Acanthaceae.

Organisation(en)

Department für Ernährungswissenschaften

Externe Organisation(en)

Corporación Verde Azul

Journal

Phytochemistry Letters

Band

10

Seiten

cxxix–cxxxii

Anzahl der Seiten

4

ISSN

1874-3900

DOI

https://doi.org/10.1016/j.phytol.2014.05.007

Publikationsdatum

05-2014

Peer-reviewed

Ja

ÖFOS 2012

301204 Pharmakognosie, 301207 Pharmazeutische Chemie, 303009 Ernährungswissenschaften

Schlagwörter

Link zum Portal

https://ucrisportal.univie.ac.at/de/publications/secundarellone-a-b-and-c-from-the-leaves-of-justicia-secunda-vahl(4fdceb74-4fec-45d8-8c00-1e4fd3217f95).html