Effects of dietary nitrate on inflammation and immune function, and implications for cardiovascular health
- Autor(en)
- Kyle Raubenheimer, Catherine Bondonno, Lauren Blekkenhorst, Karl Heinz Wagner, Jonathan M. Peake, Oliver Neubauer
- Abstrakt
Inorganic dietary nitrate, found abundantly in green leafy and some root vegeta- bles, elicits several beneficial physiological effects, including a reduction in blood pressure and improvements in blood flow through nitrate–nitrite–nitric oxide sig- naling. Recent animal and human studies have shown that dietary nitrate and ni- trite also modulate inflammatory processes and immune cell function and pheno- types. Chronic low-grade inflammation and immune dysfunction play a critical role in cardiovascular disease. This review outlines the current evidence on the efficacy of nitrate-rich plant foods and other sources of dietary nitrate and nitrite to coun- teract inflammation and promote homeostasis of the immune and vascular systems. The data from these studies suggest that immune cells and immune– vasculature interactions are important targets for dietary interventions aimed at improving, preserving, or restoring cardiovascular health.
- Organisation(en)
- Department für Ernährungswissenschaften
- Externe Organisation(en)
- Edith Cowan University, Queensland University of Technology, School of Biomedical Sciences
- Journal
- Nutrition Reviews
- Band
- 77
- Seiten
- 584-599
- Anzahl der Seiten
- 16
- ISSN
- 0029-6643
- DOI
- https://doi.org/10.1093/nutrit/nuz025
- Publikationsdatum
- 2019
- Peer-reviewed
- Ja
- ÖFOS 2012
- 303009 Ernährungswissenschaften
- Schlagwörter
- ASJC Scopus Sachgebiete
- Allgemeine Medizin
- Sustainable Development Goals
- SDG 3 – Gesundheit und Wohlergehen
- Link zum Portal
- https://ucrisportal.univie.ac.at/de/publications/765f7378-026d-4d7a-9012-9f945d7eeba4