Food-derived peroxidized fatty acids may trigger hepatic inflammation

Autor(en)
Therese Böhm, Heidi Berger, Marzieh Nejabat, Teresa Riegler, Florian Kellner, Mario Kuttke, Sandra Sagmeister, Monika Bazanella, Klaus Stolze, Anahita Daryabeigi, Nora Bintner, Michael Murkovic, Karl-Heinz Wagner, Rolf Schulte-Hermann, Nataliya Rohr-Udilova, Wolfgang Huber, Bettina Grasl-Kraupp
Abstrakt

Obesity and hepatic steatosis are frequently associated with the development of a non-alcoholic steatohepatitis (NASH). The mechanisms driving progression of a non-inflamed steatosis to NASH are largely unknown. Here, we investigated whether ingestion of peroxidized lipids, as being present in Western style diet, triggers the development of hepatic inflammation.

Organisation(en)
Department für Ernährungswissenschaften, Forschungsplattform Active Ageing
Externe Organisation(en)
Medizinische Universität Wien, Veterinärmedizinische Universität Wien, Technische Universität Graz
Journal
Journal of Hepatology
Band
59
Seiten
563-70
Anzahl der Seiten
8
ISSN
0168-8278
DOI
https://doi.org/10.1016/j.jhep.2013.04.025
Publikationsdatum
09-2013
Peer-reviewed
Ja
ÖFOS 2012
302025 Hepatologie, 303009 Ernährungswissenschaften
Sustainable Development Goals
SDG 3 – Gesundheit und Wohlergehen
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/foodderived-peroxidized-fatty-acids-may-trigger-hepatic-inflammation(7ee29e06-3420-4feb-9c77-98466b53772e).html